邢唷 > ? ? 欹 € 餜 埅 bjbj肴肴 8 墷 墷 * + + + 8 c + ? c c c !3 #3 #3 #3 #3 #3 #3 $ 6 ? . G3 i c c c c c G3 H ? u- u- u- c !3 u- c !3 u- u- u- Jf盐 + ) u- 3 ? 0 ? u- ? )- L ? u- u- ? ? c c u- c c c c c G3 G3 u- c c c ? c c c c ? c c c c c c c c c : @nL p - P L A 2 0o x - L D L N燪胈舥€≧ 仴|7hlxS舥豐 zsQ鹼剉xvz 0Xd亯0顅剉 vz@n佀唥v鴙sQ鱴乿L p - P L A 2 0'lSNO芠佀唥vo x - L D L N燪胈舥€≧ 仴|7hlxS舥豐 z剉sQ鹼0筫誰 鵞2 8 婳N3z歔媁胈迆踰€A 膥 3 2 婳3z歔媁胈迆踰€B 膥 錘蔛3 2 婳eP穅SO纇€C 膥 R+R蹚L圠 p - P L A 2 0o x - L D L 4ls^纇Km R恎燪胈舥€舥豐 zNvQ剉鴙sQ'`0觺済 N膥L p - P L A 2 0o x - L D L 4ls^鵞詋 頬_GWwQ g邁f[aIN( P < 0 . 0 5 ) A 膥0B 膥L p - P L A 2 0o x - L D L 4ls^GW>fW勜殠NC 膥 A 膥L p - P L A 2 0o x - L D L 4ls^0G e n s i n i 飝R>fW勜殠NB 膥( P < 0 . 0 5 ) P e r s o n 鴙sQR恎>f:y 燪胈舥€剉G e n s i n i 飝RGWN@nL p - P L A 2 0o x - L D L 4ls^HT>fW刢k鴙sQP < 0 . 0 5 YCQ轛R_R恎>f:y 燪胈舥€@nL p - P L A 2 0o x - L D L 4ls^鵞G e n s i n i 飝R剉豐S GWwQ g>fW剟vq_蚑P < 0 . 0 5 0觺簨 燪胈舥€剉≧ 仴|7hlxS舥豐 zN@nL p - P L A 2 0o x - L D L 4ls^ gsQ 舥豐 z妽%N蛻 RL p - P L A 2 0o x - L D L 4ls^妽貧0 0sQ.曂0@n佀唥v鴙sQ鱴乿'lSNO芠佀唥v燪胈舥≧ 仴|7hlxS舥豐 z T h e C o r r e l a t i o n R e s e a r c h b e t w e e n t h e L e v e l s o f S e r u m L i p o p r o t e i n A s s o c i a t e d P h o s p h o l i p a s e A 2 a n d O x i d i z e d L D L a n d S e v e r i t y o f A t h e r o s c l e r o s i s i n P a t i e n t s w i t h C o r o n a r y H e a r t D i s e a s e 0A b s t r a c t 0O b j e c t i v e T o i n v e s t i g a t e t h e correlation between the levels of serum lipoprotein associated phospholipase A2 (Lp-PLA2)and Oxidized LDL (ox-LDL)and severity of atherosclerosis in patients with coronary heart disease.Methods The levels of Lp-PLA2 and ox-LDL in 28 cases of patients with unstable angina pectoris (group A), 32 cases of patients with Stable angina pectoris(group B) and 32 cases of healthy subject(group C) were measured respectively. Results The differences of levels of Lp-PLA2 and ox-LDL in three groups were statistically significant (P<0.05). The levels of Lp-PLA2 and ox-LDL in group A and group B were all significantly higher than those of group C and the Gensini score, levels of Lp-PLA2 and ox-LDL in group A were all significantly higher than those of group B(P<0.05).After Person correlation analysis, the levels of Lp-PLA2 and ox-LDL of patients with CHD were positively related with Gensini score(P<0.05). Multiple regression analysis showed that, the Gensini score of patients with CHD was effected significantly by the leve l s o f L p - P L A 2 a n d o x - L D L ( P < 0 . 0 5 ) . C o n c l u s i o n T h e s e v e r i t y o f a t h e r o s c l e r o s i s i n p a t i e n t s w i t h C H D i s r e l a t e d w i t h t h e l e v e l s o f L p - P L A 2 a n d o x - L D L , t h e m o r e s e r i o u s i n a t h e r o s c l e r o s i s , t h e h i g h e r i n t h e l e v e l s o f L p - P L A 2 a n d o x - L D L . 0K e y w o r d s 0s e r u m l i p o p r o t e i n a s s o c i a t e d p h o s p h o l i p a s e A 2 ; O x i d i z e d L D L ; c o r o n a r y h e a r t d i s e a s e ; a t h e r o s c l e r o s i s ; s e v e r i t y 燪胈舥c o r o n a r y h e a r t d i s e a s e , C H D /f N蛓8^翂剉胈@垺{緐舥KN N 彇@w≧ 仭{罼_8^0@垺{T?\0@\gZ€茤錘蔛@h匭畍_c$O蚐擽I{Y蛓郪 }剉\O(u \筟f黐魜€ u胈迆踰莡秗[ 1 ] (W4N奮
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